The patent for zoxamide has recently expired, making it a promising opportunity for companies to explore and capitalize on.

Release Date:

2018-07-24

The novel pyrazole‑heterocyclic insecticide and acaricide, oxymethylenemalonate, exhibits a broad insecticidal spectrum, primarily through contact action, with no systemic activity and a long residual efficacy. In addition to its remarkable efficacy against the lepidopteran larval pest diamondback moth and thrips—members of the Thysanoptera—it also demonstrates strong activity against many other major pests that infest various crops. For example, it is effective against lepidopterans (such as cabbage moth, cabbage armyworm, beet armyworm, tea leafroller, golden‑striped leafroller, peach fruit moth, peach borer, peach leafminer, etc.), hemipterans (including peach aphid, cotton aphid, cabbage aphid, rose aphid, greenhouse whitefly,康氏粉虱, Japanese mealybug, green stink bug, brown planthopper), and thrips (including flower thrips, orange‑yellow thrips, rice yellow thrips, tobacco thrips, tea…).

　　The novel pyrazole‑heterocyclic insecticide and acaricide, oxycarboxin, boasts a broad spectrum of activity, primarily through contact action, with no systemic properties and a long residual efficacy. In addition to its outstanding efficacy against the lepidopteran larval pest diamondback moth and thrips—both members of the order Thysanoptera—it exhibits strong activity against many other major pests across a wide range of crops. Specifically, it demonstrates high control efficacy against lepidopterans (including cabbage moth, cabbage armyworm, beet armyworm, tea leafroller, golden‑striped leafroller, peach fruit moth, peach borer, peach leafminer, etc.), hemipterans (such as peach aphid, cotton aphid, cabbage aphid, rose aphid, greenhouse whitefly,康氏粉虱, Japanese mealybug, green stink bug, brown planthopper), thysanopterans (flower thrips, orange‑yellow thrips, rice yellow thrips, tobacco thrips, tea yellow thrips), coleopterans (yellow striped flea beetle, twenty‑eight‑spotted ladybird, yellow squash bug, starry sky longhorn beetle), hymenopterans (cabbage leaf wasp), dipterans (eggplant leafminer, pea leafminer, bean leafminer), as well as various mite species (tea red mite, citrus rust mite, pear leaf rust mite, tea orange leaf mite, tomato leaf mite).
　　Zoxamide is an insecticide that has attracted widespread attention from domestic companies; in 2009, Japan… Pesticide The company initially obtained provisional registration for its 98% technical‑grade active ingredient and 15% azoxystrobin emulsifiable concentrate. Subsequently, in 2016 and 2017, numerous enterprises—including U.S.-based Massey Technology, Fujian Desheng Bioengineering Co., Ltd., Liuzhou Huinong Chemical Co., Ltd., Jiangxi Huihe Chemical Co., Ltd., and Jiangxi Zhengbang Biochemical Co., Ltd.—also secured provisional registration for a range of products, including 95% azoxystrobin technical grade, 30% azoxystrobin suspension concentrate, 15% azoxystrobin suspension, 30% azoxystrobin–pymetrozine suspension, 40% butyl ether urea–azoxystrobin suspension, 12% emamectin benzoate–azoxystrobin suspension, and 9% avermectin–azoxystrobin suspension—covering both single‑ingredient and formulated insecticidal products. However, regrettably, due to the policy of revoking provisional registrations, as of May 9, 2018, all of the aforementioned azoxystrobin‑based insecticidal products had been rendered invalid.
　　Thus, it is evident that azoxystrobin is an outstanding insecticide and acaricide whose compound patent has only recently expired, making it a product well worth enterprises’ attention and market development. Although, under the new regulatory framework, the registration process for azoxystrobin‑based products has become significantly more challenging and costly compared to the previous regime, such challenges also present substantial opportunities. Moreover, when submitting applications for both the technical grade active ingredient and formulated products, applicants must provide robust documentation demonstrating aquatic safety, including advanced‑stage risk‑assessment data. All companies preparing these submissions are urged to fully appreciate this requirement.

Source: Huisheng Pesticides

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