Analysis of the Registration Status of Seed Treatments in China in 2018

Release Date:

2018-12-01

I. Number of Registrations In 2018, China registered six formulation types of seed treatment products: suspension seed coatings, dry powder seed treatments, dispersible powder seed treatments, emulsifiable seed treatments, suspension seed treatments, and liquid seed treatments. Among these, there were 94 registrations for suspension seed coatings, 4 for dry powder seed treatments, 7 for dispersible powder seed treatments, 1 for emulsifiable seed treatment, 9 for suspension seed treatments, and 2 for liquid seed treatments. Clearly, suspension seed coatings accounted for the largest number of registrations. As of the latest available date, a total of 11 seed treatment products had been registered in China.

I. Number of Registrations

In 2018, China seed There are six dosage forms for formulation registration: suspension seed coating agents, seed Handling dry powder formulations, seed Handling dispersible powders, seed Handling emulsions, seed Handling suspending agents, seed Processing liquid formulations. Among these, the number of registered suspension seed coatings is 94. seed The number of registered dry powder formulations is four. seed The number of registrations for dispersible powder formulations is 7. seed The number of emulsion registrations processed is 1. seed The number of suspended‑agent registrations processed is 9. seed The number of registered liquid formulations is two. As can be seen, suspension‑type seed coatings account for the largest share of registrations.

As of the deadline, China has registered seed There are a total of 117 treatment agents, including 48 single‑component products and 69 formulated mixtures. As such, the number of registered mixtures exceeds that of single‑component products.

II. Registration of Active Ingredients and Formulation

As of the date hereof, those that have obtained registration are… seed The active ingredients of the treatment agent include Bacillus subtilis, thiamethoxam, imidacloprid, difenoconazole, metalaxyl‑M, fludioxonil, silthiopham, and pendimethalin.

Zoxamide, tebuconazole, pyraclostrobin, thiamethoxam, dinotefuran, and others; single‑ingredient formulations are listed in Table 1, while mixed‑formulation registrations are presented in Table 2.

III. seed Issues to Consider When Registering Efficacy Data for Treatment Agents

1. Reasonableness of the product formulation

The content of the active ingredient shall comply with registration requirements, such as when it contains fipronil. seed The content of fipronil in the treatment agent shall comply with the specified limits.

2. The safety assessment of indoor crops shall comply with the relevant requirements.

Experimental Design seed The methods for assessing the safety of treatment agents to indoor crops should refer to “…” Pesticide Part 3 of the Criteria for Evaluating Crop Safety: seed “Laboratory Test Method for Evaluating the Crop Safety of Treatment Agents” (NY/T 1965.3-2013), rather than “ Pesticide Part 1 of the Guidelines for Crop Safety Assessment: Laboratory Tests for Evaluating the Crop Safety of Fungicides and Insecticides

Methods. The most significant difference between the two is that the former requires the establishment of four test doses: the highest field efficacy dose recommended by the manufacturer, along with 1.5-, 2-, and 2.5-fold multiples of that dose.

3. The selection of target organisms for indoor bioassay tests shall comply with the relevant requirements.

Appropriate test targets should be selected based on the characteristics of the fungicide; for example, root rot can be caused by a variety of pathogens, including Pythium, Fusarium, and Phytophthora. For broad-spectrum agents, it may suffice to select only one of these pathogens.

A pathogenic fungus is used in the assay; however, when the product formulation contains active ingredients such as fludioxonil or metalaxyl‑M, the test target should not be limited to Fusarium species that are unaffected by these compounds.

Fungi should also include Pythium or Phytophthora.

4. The experimental design for formulation screening shall comply with the relevant requirements.

The experimental design should be rationally tailored to the intended purpose of the formulation, such as a ternary mixture comprising one insecticide and two fungicides. seed For the treatment agents, indoor bioassays for insecticidal activity and indoor formulation screening for two fungicides must be conducted separately, followed by an assessment of whether antagonistic interactions exist among the different components.

5. Field efficacy trial designs shall comply with the relevant requirements.

Primarily, the selection of reference formulations and test dosage levels fails to meet the requirements for evaluation. Generally speaking, for single‑component products, a locally commonly used single‑component formulation should be designated as the control; for formulated mixtures, each individual component and the corresponding…

The locally commonly used pesticide shall serve as the control; the dose of the control formulation should be the locally recommended standard rate.

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